Membrane glycoprotein folding, oligomerization and intracellular transport: effects of dithiothreitol in living cells.
نویسندگان
چکیده
منابع مشابه
Membrane protein folding and oligomerization: the two-stage model.
We discuss the view that the folding of many, perhaps most, integral membrane proteins can be considered as a two-stage process. In stage I, hydrophobic alpha-helices are established across the lipid bilayer. In stage II, they interact to form functional transmembrane structures. This model is suggested by the nature of transmembrane segments in known structures, refolding experiments, the asse...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 1993
ISSN: 0261-4189
DOI: 10.1002/j.1460-2075.1993.tb05863.x